A Secret Weapon For ceesdekker

A Secret Weapon For ceesdekker

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Making use of single-molecule optical and AFM imaging and drive-spectroscopy tactics, we seek out to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our exploration pursuits contain:

1996, initially mesoscopic charge density waves units; and to start with electrical measurements on just one steel nanocluster concerning nanoelectrodes

Back in 1991, Sumio Iijima of the NEC Corporation experienced reported the synthesis of carbon nanotubes. Band structure calculations suggested that these nanotubes could exhibit metallic band conduction. This would be a significant advantage more than the conducting polymers we had explored, which were, in fact, disordered semiconductors providing merely variable-range hopping conductivity.

Due to the fact 2000, Dekker has shifted the primary emphasis of his work in the direction of biophysics where by he scientific tests the Houses of single biomolecules and cells using the instruments of nanotechnology. This transformation of discipline was pushed by his fascination to the extraordinary functioning of biological molecular structures, and also via the long-phrase point of view that numerous interesting discoveries could be predicted With this industry.[five] Current lines of study in his biophysics team are during the parts of:[six]

This yielded a breakthrough. Within just a few months, we were ready to measure transportation by means of somebody single-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological know-how with the Lively analysis lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes have been genuine quantum wires with really extensive (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.

Our exploration ranges within the biophysics of DNA to artificial cells and beyond. ceesdekker.net Remember to take a look underneath at the spectrum of our present tasks.

Lots of similar developments adopted, where our team established different transistor variants like single-electron transistors at space temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled numerous transistors into tiny proof-of-principle electronic circuits.

Instance (1) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is revealed in gray, the rim in the pore is highlighted in red, along with a 3D rendering on the motion on the DNA rod is displayed.

What if, instead of working with traditional major-down silicon electronics, transistors may very well be built from The underside up making use of one organic and natural molecules since the switching aspects? This idea, which became The idea of these days’s subject of molecular electronics, initial emerged during the 1970s.

Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-building system

‘The idea that There's this type of matter as a beginning, an enormous bang, is previously a fascinating signpost to consider that there was a creator. But more usually, and on the basis of pure rationality, I also arrive at a Christian interpretation of actuality. An atheistic worldview can be a naturalistic worldview: essentially, there are actually only atoms and natural forces that we are able to measure.

Later on we spoke again briefly since Dekker felt that our dialogue of his religion immediately became purely philosophical, whereas Furthermore, it concretely allows him in his work.

Let’s very first search back again at this time when you decided to shift your focus from superconductivity and nanotubes to biology at the end of the 1990s.

2004, discovery of latest physics in translocation of DNA by means of nanopores; first experimental review of ions conduction in nanofluidic channels; very first electrochemistry with individual one-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization from the mechanical Attributes of double-stranded RNA; and very first one-molecule examine of DNA translocation by a restriction-modification enzyme.